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Brush & floss

How to Choose a Toothpaste (and Three Good Options)

Fluoride, the ADA Seal, whitening and sensitivity pastes explained, and what to ignore on the packaging.

Updated October 21, 2026 · Contains affiliate links

Walk down the toothpaste aisle and you’ll see whitening, charcoal, natural, sensitivity, tartar control. Most of it is marketing. A few things matter.

What actually matters

  1. Fluoride. This is the main ingredient proven to prevent cavities. If a toothpaste doesn’t contain it, skip it, however natural it sounds.
  2. The ADA Seal of Acceptance. The American Dental Association gives its Seal to products whose safety and effectiveness claims it has reviewed. It’s a useful shortcut. Check the box, because products and formulas change.
  3. Low abrasiveness. A toothpaste that’s too abrasive can wear enamel, especially if you brush hard. Many whitening pastes are more abrasive.

What’s mostly marketing

Match it to your needs

If you have… Look for
No special issues A fluoride toothpaste with the ADA Seal
Sensitive teeth A desensitizing paste; see tooth sensitivity
Enamel erosion or reflux A fluoride paste designed for enamel protection
Gum problems Ask your dentist; stannous fluoride pastes can help
Frequent cavities Ask your dentist about a higher-fluoride prescription paste

How much to use

A pea-sized amount for adults and children over three. A smear the size of a grain of rice for children under three. See the full brushing method.

Don’t overthink it

The best toothpaste is a fluoride one you’ll use twice a day for two full minutes. The flavor you like beats the one with a longer list of claims.

Our picks

Picks marked Research pick are chosen from spec comparisons and large-sample owner reviews. We switch a pick to Tested by us only after we've used it. Prices change, so check the current one.

Best all-around daily toothpaste

1.Colgate Total

Research pick

A mainstream fluoride toothpaste formulated with stannous fluoride, which also helps with plaque and gum health. A sensible default for most adults. Check the current packaging to confirm it carries the ADA Seal.

  • Fluoride with added gum and plaque protection
  • Inexpensive and everywhere
  • Some people dislike the taste
  • Stannous fluoride can stain teeth slightly in some people
Check price on Amazon →
Best alternative stannous-fluoride paste

2.Crest Pro-Health

Research pick

Another stannous fluoride toothpaste aimed at plaque, gum health and sensitivity. A good one to try if you want to compare against Colgate Total.

  • Fluoride and gum-health formulation
  • Mild flavor options
  • Flavor and texture are personal
  • Check the label for the specific version
Check price on Amazon →
Best if you worry about enamel wear

3.Sensodyne Pronamel

Research pick

A fluoride toothpaste made to help strengthen enamel against acid erosion, aimed at people who have acid reflux, drink a lot of citrus or soda, or whose enamel is worn.

  • Targets acid erosion
  • Gentle on sensitive teeth
  • Costs more than basic fluoride paste
  • Not a whitening toothpaste
Check price on Amazon →